About Us

 

King's Clinical Trials Unit at King's Health Partners:

The King’s Clinical Trials Unit (CTU) helps research teams throughout the country carry out clinical trials safely and to a high scientific standard, and offers a range of services to help ensure the results are accurate and credible. The Unit’s services are available to researchers, throughout King’s Health Partners (KHP) and also across the UK.

 

The CTU is part of the Department of Biostatistics and is led by Professor Andrew Pickles, Head of Department and Professor of Biostatistics and Psychological Methods. The KCTU Unit Manager is Caroline Murphy a qualified nurse by training who specialised in neuroscience and palliative care before working as a research nurse and trial manager on a number of both commercial and academic-led projects both in the UK and internationally.

To find out more about these services please contact the CTU using the details on the ‘Contact Us’ page.

KCTU SERVICES 

The King's Clinical Trials Unit can now offer comprehensive support to trials across all disease areas in King's Health Partners which are funded by NIHR HTA, NIHR EME, NIHR SDO, NIHR PHR, NIHR HSR. Other trials may be accepted onto the portfolio for comprehensive support on a case by case basis - please contact Caroline Murphy at caroline.murphy@kcl.ac.uk to discuss.

The CTU offers a competitively priced discrete services (see below, such as web based randomisation or web based electronic data capture using the InferMed MACRO system) which any trial across King's Health Partner or externally may access. 

Protocol development:

  • Study design
  • Protocol writing
   
Randomisation:
  • 24-hour Online randomisation
  • Online minimisation
   
Data management:
  • Data management plan preparation
  • CRF creation
  • Database design
  • Web based remote data entry system
  • Integrated data validation checks
  • Data query management
  • Report preparation
   
Pharmacovigilence:
  • SAE report management
  • Annual safety report preparation
   
IMP Management
  • IMP supply advice
  • Costing IMP supply
  • Planning study requirements
   
Trial management:
  • Ethics applications
  • Annual progress reports
  • MHRA applications
  • Contracts management
  • Site initiation visits
  • Monitoring services
  • Report preparation
  • Trial master file management
   
Statistical services:
  • Sample size calculations
  • Response to reviewers
  • Report preparation
  • Statistical analysis
  • Contribution to primary papers
   
Education / training:
  • Trial manager supervision
  • Data manager supervision

 

For further information please see:

 

A selection of KCTU publications:

MENOS Trial (2012) The Lancet Oncology, 15 February, DOI: 10.1016/S1470-2045(11)70364-3

SADD Trial (2011) The Lancet, Volume 378, Issue 9789, Pages 403-411, 30 July

PACE Trial (2011) The Lancet, Volume 377, Issue 9768, Pages 823-836, 5 March

RIOTT Trial (2010) The Lancet, Volume 375, Issue 9729, Pages 1885-1895, 29 May

RMC Trial (2009) The Lancet Neurology, Volume 8, Issue 2, Pages 158-164, February

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Contact Us

The King's CTU is part of the Department of Biostatistics and has been awarded full CTU registration by the UK Clinical Research Collaboration (UKCRC)

Write to us at :
Clinical Trials Unit, King's College London
PO64, Room M2.06
Institute of Psychiatry
16 De Crespigny Park
London SE5 8AF

Phone/Fax/Email :
Phone: 020 7848 0532
Fax: 020 7848 5229
Email: ctusupport@iop.kcl.ac.uk